Gorilla Glue #4: Complete UK Patient Guide

Gorilla Glue #4 — What UK Patients Need to Know

Gorilla Glue #4 (GG4, also known as Original Glue) is one of the most prescribed and widely recognised strains in UK medical cannabis. Named for its incredibly sticky resin that "glues" scissors during trimming, GG4 is known for powerful, long-lasting effects that have made it a favourite for patients with severe chronic pain, insomnia, and high-tolerance conditions.

The Basics

• Type: Indica-dominant hybrid (70% Indica / 30% Sativa)
• THC: 22–28% (one of the highest available on UK prescription)
• CBD: Under 1%
• Primary terpenes: Caryophyllene, Myrcene, Limonene, Humulene
• Flavour: Earthy, pine, sour, chemical undertones
• Appearance: Dense, frosty, dark green buds with heavy white trichome coating

Effects

Physical Effects

• Heavy full-body relaxation — progressive from onset
• Strong muscle tension relief
• Couch-lock at standard doses — plan for limited mobility
• Powerful sedation at higher doses
• Appetite stimulation (significant)

Mental Effects

• Initial euphoria and mental "uplift" that transitions to heavy relaxation
• Thought quietening — useful for anxiety and rumination
• Cerebral haziness at higher doses
• Not recommended for daytime use or tasks requiring focus

Medical Uses

GG4 is particularly popular for:

• Severe chronic pain: One of the strongest analgesics available on UK prescription
• Treatment-resistant insomnia: High myrcene content promotes deep, long sleep
• PTSD with hyperarousal: Thought quietening and sedation highly effective
• Muscle spasticity (MS): Strong muscle relaxant
• High-tolerance patients: For patients who have not responded to lower-THC products

Terpene Profile and Why It Matters

GG4 is caryophyllene-dominant, which contributes significantly to its anti-inflammatory and anti-anxiety properties beyond just THC. The combination of caryophyllene (binding CB2 receptors) and myrcene (CB1 sedation) creates a uniquely effective profile for pain and sleep.

Key terpenes in GG4:

• Caryophyllene (1.2–1.8%): Anti-inflammatory, anxiety reduction, CB2 agonist
• Myrcene (0.8–1.4%): Sedation, muscle relaxation, sleep promotion
• Limonene (0.4–0.8%): Initial mood lift before sedation sets in
• Humulene (0.3–0.6%): Anti-inflammatory, appetite modulation

Dosing Guidance for UK Patients

GG4's high THC content means careful titration is essential, especially for new patients:

1. New patient: 0.05–0.1g vaporised, evening only. Wait 15–20 minutes between puffs.
2. Experienced patient: 0.1–0.3g per session, 1–2 sessions per day maximum
3. High-tolerance patient: As prescribed, typically 0.3–0.6g per session

Do not use GG4 before driving, operating machinery, or performing tasks requiring concentration. Plan for 4–6 hours of significant impairment at typical doses.

Side Effects to Be Aware Of

• Dry mouth (significant — stay well hydrated)
• Dry, red eyes
• Anxiety or paranoia if dose is too high (reduce dose if this occurs)
• Short-term memory impairment during effect
• Dizziness, particularly standing up (orthostatic hypotension)

Where to Get GG4 on a UK Prescription

Gorilla Glue #4 is available from several UK manufacturers including Curaleaf International and Aurora. Prices vary across clinics — compare current prices on LeafMe before your prescription is finalised. The same GG4 product can vary by £20–£40 per 10g across different dispensing clinics.